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 Shandong Haohong Biotechnology Co., Ltd.

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HomeProductsActive Pharmaceutical Ingredient(API)Ponatinib API

Ponatinib API (Total 2 Products)

Product categories of Ponatinib API, we are specialized manufacturers from China, Ponatinib Api, Ponatinib Cas 943319-70-8 suppliers/factory, wholesale high-quality products of Ap24534 Ponatinib Cs-165 R & D and manufacturing, we have the perfect after-sales service and technical support. Look forward to your cooperation!
Top Quality Best Price Ponatinib API Cas 943319-70-8

Unit Price: USD 1 / Kilogram

Min.Order Unit Price
1 Kilogram USD 1 / Kilogram

Brand: HAOHONG

Packaging: PE BAG+Aluminum foil bag+FIBRE DRUM

Supply Ability: 100KG/MONTH

Product Name Ponatinib AP24534 Ponatinib Iclusig PONATINIB 3 2 Imidazo 1 2 b pyridazin 3 yl ethynyl 4 methyl N 4 4 methylpiperazin 1 yl methyl 3 trifluoromethyl phenyl benzamide 3 imidazo 1 2 b pyridazin 3 ylethynyl 4 methyl N 4 4 methylpiperazin 1...
Ponatinib API Cas 943319-70-8

Brand: HAOHONG

Packaging: PE BAG+Aluminum foil bag+FIBRE DRUM

Supply Ability: 100KG/MONTH

Product Name Ponatinib AP24534 Ponatinib Iclusig PONATINIB 3 2 Imidazo 1 2 b pyridazin 3 yl ethynyl 4 methyl N 4 4 methylpiperazin 1 yl methyl 3 trifluoromethyl phenyl benzamide 3 imidazo 1 2 b pyridazin 3 ylethynyl 4 methyl N 4 4 methylpiperazin 1...

China Ponatinib API Suppliers

Ponatinib is an orally bioavailable multitargeted receptor tyrosine kinase (RTK) inhibitor with potential antiangiogenic and antineoplastic activities. Ponatinib inhibits unmutated and all mutated forms of Bcr-Abl, including T315I, the highly drug therapy-resistant missense mutation of Bcr-Abl. This agent also inhibits other tyrosine kinases including those associated with vascular endothelial growth factor receptors (VEGFRs) and fibroblast growth factor receptors (FGFRs); in addition, it inhibits the tyrosine kinase receptor TIE2 and FMS-related tyrosine kinase receptor-3 (Flt3). RTK inhibition by ponatinib may result in the inhibition of cellular proliferation and angiogenesis and may induce cell death. Bcr-Abl is a fusion tyrosine kinase encoded by the Philadelphia chromosome.

Ponatinib is a tyrosine kinase receptor inhibitor that is used in the therapy of refractory chronic myelogenous leukemia (CML) positive for the Philadelphia chromosome. Ponatinib is commonly associated with transient elevations in serum aminotransferase levels during treatment, but with only rare instances of clinically apparent acute liver injury.

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