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 Shandong Haohong Biotechnology Co., Ltd.

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HomeProductsAnti-cancer DrugRucaparib Intermediates

Rucaparib Intermediates (Total 2 Products)

Product categories of Rucaparib Intermediates, we are specialized manufacturers from China, Rucaparib Cas 78902-09-7, Rucaparib Cas 2913-97-5 suppliers/factory, wholesale high-quality products of Rucaparib Intermediate Cas 78902-09-7 R & D and manufacturing, we have the perfect after-sales service and technical support. Look forward to your cooperation!
Rucaparib Intermediate Cas 78902-09-7

Brand: HAOHONG

Packaging: PE BAG+Aluminum foil bag+FIBRE DRUM

Supply Ability: 30MT/MONTH

Product Name PHTHALIMIDOACETALDEHYDE DIETHYL ACETAL phthalimido acetaldehyde hydrate phthalimidoacetaldehyde diethylacetal N phthalimido aminoacetaldehyde diethyl acetal 2 2 2 diethoxyethyl isoindoline 1 3 dione 2 Phthalimidylacetaldehyde diethyl...
Rucaparib Intermediate Cas 2913-97-5

Brand: HAOHONG

Packaging: PE BAG+Aluminum foil bag+FIBRE DRUM

Supply Ability: 30MT/MONTH

Product Name 2 1 3 dioxoisoindol 2 yl acetaldehyde N Phthalylaminoacetaldehyde Phthalimidoacetaldehyde 1 3 DIOXO 1 3 DIHYDRO 2H ISOINDOL 2 YL ACETALDEHYDE Phthalylglycine aldehyde 1 3 dihydro 1 3 dioxo 2H isoindole 2 acetaldehyde API name Rucaparib...

China Rucaparib Intermediates Suppliers

Rucaparib is an orally bioavailable tricyclic indole and inhibitor of poly(ADP-ribose) polymerases (PARPs) 1 (PARP1), 2 (PARP2) and 3 (PARP3), with potential chemo/radiosensitizing and antineoplastic activities. Upon administration, rucaparib selectively binds to PARP1, 2 and 3 and inhibits PARP-mediated DNA repair. This enhances the accumulation of DNA strand breaks, promotes genomic instability and induces cell cycle arrest and apoptosis. This may enhance the cytotoxicity of DNA-damaging agents and reverse tumor cell resistance to chemotherapy and radiation therapy. PARPs are enzymes activated by single-strand DNA breaks that catalyze the post-translational ADP-ribosylation of nuclear proteins, which induces signaling and the recruitment of other proteins to repair damaged DNA. The PARP-mediated repair pathway plays a key role in DNA repair and is dysregulated in a variety of cancer cell types.

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