Communicate with Supplier? Supplier
Kelly Ms. Kelly
What can I do for you?
+8613375313165
Chat Now
Chat Now Contact Supplier

 Shandong Haohong Biotechnology Co., Ltd.

All
  • All
  • Title
All
  • All
  • Title
HomeProductsPAH DrugsMacitentan Intermediate

Macitentan Intermediate (Total 7 Products)

Product categories of Macitentan Intermediate, we are specialized manufacturers from China, Macitentan Intermediate 146533-41-7, Macitentan Intermediate 706811-25-8 suppliers/factory, wholesale high-quality products of Macitentan Intermediate 147962-41-2 R & D and manufacturing, we have the perfect after-sales service and technical support. Look forward to your cooperation!
High quality Macitentan Intermediate Cas 146533-41-7

Unit Price: USD 1 / Kilogram

Min.Order Unit Price
1 Kilogram USD 1 / Kilogram

Brand: HAOHONG

Packaging: PE BAG+Aluminum foil bag+FIBRE DRUM

Supply Ability: 30MT/MONTH

Product Name 5 4 Bromophenyl 4 6 dichloropyrimidine PyriMidine 5 4 broMophenyl 4 6 dichloro 5 4 broMophenyl 4 6 dichloropyriMidine 5 4 Bromophenyl 4 6 dichloro Pyrimidin 5 4 broMopheChemicalbooknyl 4 MacitentanIntermediate1 QC 9668 We Shandong...
Macitentan Intermediate Cas 1642873-03-7

Brand: HAOHONG

Packaging: PE BAG+Aluminum foil bag+FIBRE DRUM

Supply Ability: 30MT/MONTH

Product Name N Propylsulfuric diamide sodium Sulfamide N propyl sodium salt 1 1 We Shandong Haohong Biotechnology Co Ltd are manufacture of API and intermediates Macitentan is our top strong project API name Macitentan Intermediate CAS No 1642873 03...
Macitentan Intermediate Cas 1393813-42-7

Brand: HAOHONG

Packaging: PE BAG+Aluminum foil bag+FIBRE DRUM

Supply Ability: 30MT/MONTH

Product Name N 5 4 bromophenyl 6 chloropyrimidin 4 yl propane 1 sulfamide N 5 4 bromophenyl 6 chloro 4 pyrimidinyl N propylsulfamide SulfaMide N 5 4 broMophenyl 6 chloro 4 pyriMidinyl N propyl We Shandong Haohong Biotechnology Co Ltd are manufacture...
Macitentan Intermediate Cas 1393813-41-6

Brand: HAOHONG

Packaging: PE BAG+Aluminum foil bag+FIBRE DRUM

Supply Ability: 30MT/MONTH

Product Name Propylsulfamide potassium Sulfamide N propyl potassium salt 1 1 We Shandong Haohong Biotechnology Co Ltd are manufacture of API and intermediates Macitentan is our top strong project API name Macitentan Intermediate CAS No 1393813 41 6...
Macitentan Intermediate Cas 147962-41-2

Brand: HAOHONG

Packaging: PE BAG+Aluminum foil bag+FIBRE DRUM

Supply Ability: 30MT/MONTH

Product Name 1 sulfamoylamino propane Sulfamide propyl N propylsulfamide Propylsulfamide We Shandong Haohong Biotechnology Co Ltd are manufacture of API and intermediates Macitentan is our top strong project API name Macitentan Intermediate CAS No...
Macitentan Intermediate Cas 706811-25-8

Brand: HAOHONG

Packaging: PE BAG+Aluminum foil bag+FIBRE DRUM

Supply Ability: 30MT/MONTH

Product Name 5 4 bromophenyl pyrimidine 4 6 diol 5 4 bromophenyl pyrimidine 4 6 diol Oxazole 5 4 bromophenyl 5 4 bromophenyl oxazole We Shandong Haohong Biotechnology Co Ltd are manufacture of API and intermediates Macitentan is our top strong...
Macitentan Intermediate Cas 146533-41-7

Brand: HAOHONG

Packaging: PE BAG+Aluminum foil bag+FIBRE DRUM

Supply Ability: 30MT/MONTH

Product Name 5 4 Bromophenyl 4 6 dichloropyrimidine PyriMidine 5 4 broMophenyl 4 6 dichloro 5 4 broMophenyl 4 6 dichloropyriMidine 5 4 Bromophenyl 4 6 dichloro Pyrimidin 5 4 broMopheChemicalbooknyl 4 MacitentanIntermediate1 QC 9668 We Shandong...

China Macitentan Intermediate Suppliers

Macitentan is an orally available dual endothelin receptor (ETR) antagonist with potential antihypertensive and antineoplastic activity. Upon administration, macitentan and its metabolites block the binding of endothelin isoform 1 (ET-1) to type-A and type-B ETR on both the tumor cells and the endothelial cells in the tumor vasculature. This prevents ET-1 mediated signaling transduction which may decrease tumor cell proliferation, progression, and angiogenesis in tumor tissue. ET-1, a potent vasoconstrictor that plays an important role in inflammation and tissue repair, is, together with its receptors, overexpressed varyingly in many tumor cell types.

Macitentan is an endothelin receptor antagonist that is used in the therapy of pulmonary arterial hypertension (PAH). Macitentan has been associated with a low rate of serum enzyme elevations during therapy, but has yet to be implicated in cases of clinically apparent acute liver injury.

Macitentan is a member of the class of sulfamides in which the two amino groups of sulfonamide are substituted by 5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl and propyl groups. An orphan drug used for the treatment of pulmonary arterial hypertension. It has a role as an endothelin receptor antagonist, an antihypertensive agent and an orphan drug. It is an organobromine compound, a member of pyrimidines, an aromatic ether, a ring assembly and a member of sulfamides. It derives from an ethylene glycol and an ACT-132577.

Home

Product

Whatsapp

About Us

Inquiry