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 Shandong Haohong Biotechnology Co., Ltd.

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HomeProductsActive Pharmaceutical Ingredient(API)Ponatinib APITop Quality Ponatinib API

Top Quality Ponatinib API

  • $1
    ≥1
    Kilogram
Payment Type:
L/C,T/T,Paypal,Western Union
Incoterm:
FOB,CIF,CPT,CIP
Min. Order:
1 Kilogram
Transportation:
Ocean,Air
Port:
NANJING PORT,SHANGHAI PORT,BEIJING PORT
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  • Product Description
Overview
Product Attributes

Model No.Cas 943319-70-8

BrandHAOHONG

place of originChina

Types ofPharmaceutical Intermediates

Phasical StateSolid Powder

PSA65.77000

LOGP4.40480

ColorLight Yellow

CAS No.943319-70-8

Molecular FormulaC29H27F3N6O

Molecular Weight532.55900

Density1.292 G/cm3

Supply Ability & Additional Informations

PackagingPE BAG+Aluminum foil bag+FIBRE DRUM

Productivity1MT/YEAR

TransportationOcean,Air

Place of OriginSHANDONG,CHINA

Supply Ability100KG/MONTH

PortNANJING PORT,SHANGHAI PORT,BEIJING PORT

Payment TypeL/C,T/T,Paypal,Western Union

IncotermFOB,CIF,CPT,CIP

Packaging & Delivery
Selling Units:
Kilogram
Package Type:
PE BAG+Aluminum foil bag+FIBRE DRUM

Product Name:

Ponatinib;

AP24534(Ponatinib);

Iclusig;

PONATINIB;

3-(2-(Imidazo[1,2-b]pyridazin-3-yl)ethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide;

3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide;

3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide;


Ponatinib (trade name Iclusig, previously AP24534) is an oral drug developed by ARIAD Pharmaceuticals for the treatment of chronic myeloid leukemia (CML) and Philadelphia chromosome–positive (Ph+) acute lymphoblastic leukemia (ALL). It is a multi-targeted tyrosine-kinase inhibitor. Some forms of CML, those that have the T315I mutation, are resistant to current therapies such as imatinib. Ponatinib has been designed to be effective against these types of tumors.

The United States Food and Drug Administration approved the drug as a candidate in December 2012, but temporarily suspended sales on 31 October 2013 because of "the risk of life-threatening blood clots and severe narrowing of blood vessels". This suspension was partially lifted on Dec. 20, 2013 with ponatinib being issued revised prescribing information, a new "Black Box Warning" and a "Risk Evaluation and Mitigation Strategy" in place to better evaluate the risks and benefits of using the drug.

In the US it can cost $138,000 a year which has been criticised.


We, Shandong Haohong Biotechnology Co., Ltd. are manufacture of API and intermediates, Ponatinib is our top strong project.

API name: Ponatinib Intermediate CAS No.: 943319-70-8


We can offer best quality product with perfect service, full documents support, factory audit is availbale.


Purity HPLC:> 99%

Water contents :< 1.0%

Packing and Storage: Preserve in well-closed containers, and store at room temperature.


Ponatinib Cas 943319-70-8

Our Ponatinib intermediate list is as following, we have all the below intermedites offering all year.

Ponatinib


Here are some other items for your checking:

Cabozantinib Intermediate;Bicalutamide Intermediate;Empagliflozin Intermediate;

Enzalutamide Intermediate;Apalutamide Intermediate;Alectinib Intermediate


Package & Shipping:

1. Preferentially DHL or FedEx for quantity less than 50KG; Air shipping for 100KG above; Sea shipping for quantity over 500KG.
2. We can offer complete package from concept to delivery; arranging everything up until products arrive at your own door or distribution hub.

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Our Service:

1. Supply high quality products with reasonable prices for pharmaceutical factory.
2. In time delivery, Packing pictures and loading video before loading.
3. Various documents(COA, MSDS, ROS, MOA etc.) and factory audit available.
4. Pre-sale consultation and post-sale service available.
5. Provide market informations to make customers fully informed.




Product Categories : Active Pharmaceutical Ingredient(API) > Ponatinib API

Company Overview
Shandong Haohong Biotechnology Co., Ltd. is located in Provincial Chemical Industrial Park of Liaocheng city, Shandong province, which is a beautiful water city. The total production area is around 130 thousand square meters, with 40 employees and 12 R&D technicians. Our company focuses on the development and production of pharmaceutical products, with 13 sets of 50L to 5000L reactors, and the annual manufacturing capacity can up to 500 tons. We had advanced sewage treatment system, with the daily processing capacity of 1000 tons. The new R&D laboratory is located on the 4th floor of the accelerator middle section of Qilu Science and Technology Town, Qilu High-tech Development Zone, Shandong Province, and is located in a large modern ecological science and technology park in Qihe Science and Technology City of Zhongguancun Haidian Park. Our company mainly focuses on the development of anti-cancer, anti-diabets series of API and its advanced intermediates. The main products include Bicalutamide, enzalutamide, apalutamide, macitentan, cabozantinib, ceritinib, empagliflozin, tofacitinib citrate, and alectinib,etc. In line with the concept of "truth-seeking, innovation and integrity", we had exported our products to the United States, European countries, Japan, India, Bangladesh and other overseas markets. At present, Our company has dozens of advanced intermediates, all of which are commercialized, and at the same time, we can provide customers with efficient customized synthesis services from grams to 100 kilograms. We will continue to provide high quality products with most competitive prices and good service to customers all over the world. We sincerely hope to establish stable and strategic business relationships with customers from home and abroad.
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