Ruxolitinib; 941678-49-5; INCB018424; Ruxolitinib (INCB018424); (R)-3-(4-(7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)-1H-Pyrazol-1-Yl)-3-Cyclopentylpropanenitrile; INCB-018424; INCB 018424; UNII-82S8X8XX8H;

China Ruxolitinib Intermediates Suppliers

Ruxolitinib is an orally bioavailable Janus-associated kinase (JAK) inhibitor with potential antineoplastic and immunomodulating activities. Ruxolitinib specifically binds to and inhibits protein tyrosine kinases JAK 1 and 2, which may lead to a reduction in inflammation and an inhibition of cellular proliferation. The JAK-STAT (signal transducer and activator of transcription) pathway plays a key role in the signaling of many cytokines and growth factors and is involved in cellular proliferation, growth, hematopoiesis, and the immune response; JAK kinases may be upregulated in inflammatory diseases, myeloproliferative disorders, and various malignancies.

Ruxolitinib is a Janus kinase inhibitor that is used in the treatment of intermediate or high risk myelofibrosis and resistant forms of polycythemia vera and graft-vs-host disease. Ruxolitinib is associated with transient and usually mild elevations in serum aminotransferase during therapy and to rare instances of self-limited, clinically apparent idiosyncratic acute liver injury and to cases of reactivation of hepatitis B in susceptible individuals.

China leading manufacturers and suppliers of Ruxolitinib; 941678-49-5; INCB018424; Ruxolitinib (INCB018424); (R)-3-(4-(7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)-1H-Pyrazol-1-Yl)-3-Cyclopentylpropanenitrile; INCB-018424; INCB 018424; UNII-82S8X8XX8H;Ruxolitinib Intermediate Cas 1029716-44-6,Cas 269410-08-4 Pharmaceutical Raw Material,Ruxolitinib Intermediate Cas 1236033-21-8,Ruxolitinib Intermediate Cas 2075-45-8,Ruxolitinib Intermediate Cas 941685-26-3,Ruxolitinib Intermediate Cas 591769-05-0,etc.

Pharmaceutical Raw Material 1029716-44-6,Ruxolitinib Intermediate Cas No.1029716-44-6,High Purity Ruxolitinib Intermediate 1029716-44-6;

Ruxolitinib Intermediate Cas 269410-08-4,4 Pyrazoleboronic Acid Pinacol Ester 97%,Ruxolitinib Intermediate Offering;

Ruxolitinib Intermediate Cas No.1236033-21-8,Pharmaceutical Ruxolitinib Intermediate,Pharmaceutical Raw Material Cas 1236033-21-8;Ruxolitinib Intermediate Cas No.2075-45-8.

Min.Order	Unit Price
1 Kilogram	USD 1 / Kilogram

Min.Order	Unit Price
1 Kilogram	USD 1 / Kilogram

Min.Order	Unit Price
1 Kilogram	USD 1 / Kilogram

Min.Order	Unit Price
1 Kilogram	USD 1 / Kilogram

Min.Order	Unit Price
1 Kilogram	USD 1 / Kilogram

Ruxolitinib Intermediates

Ruxolitinib Intermediate Cas 1029716-44-6

Cas 269410-08-4 Pharmaceutical Raw Material

Ruxolitinib Intermediate Cas 1236033-21-8

Pharmaceutical Raw Material Cas 1236033-21-8

Ruxolitinib Intermediate Cas 2075-45-8

Ruxolitinib Intermediate Cas 269410-08-4

Ruxolitinib Intermediate Cas 941685-26-3

Ruxolitinib Intermediate Cas 941685-27-4

Ruxolitinib Intermediate Cas 591769-05-0

Pharmaceutical Raw Material Intermediates CAS 941685-26-3