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 Shandong Haohong Biotechnology Co., Ltd.

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HomeProductsAnti-cancer DrugAbemaciclib Intermediates
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Abemaciclib Intermediates

(Total 5 Products)
Abemaciclib Intermediate Cas 67567-26-4

Unit PriceUSD 1 / Kilogram

Min.Order Unit Price
1 Kilogram USD 1 / Kilogram

Brand: HAOHONG

Packaging: PE BAG+Aluminum foil bag+FIBRE DRUM

Supply Ability: 30MT/MONTH

Product Name: 4-Bromo-2,6-difluoroaniline; 4-bromo-2,6-difluorobenzenamine; 2,6-difluoro-4-bromoaniline; BENZENAMINE,4-BROMO-2,6-DIFLUORO; 4-bromo-2,6-difluorophenylamine; 4-bromo-2,6-difluoro-aniline; 4-Bromo-2,6-difluoroaniline is used in the...
Abemaciclib Intermediate Cas 1231930-33-8

Unit PriceUSD 1 / Kilogram

Min.Order Unit Price
1 Kilogram USD 1 / Kilogram

Brand: HAOHONG

Packaging: PE BAG+Aluminum foil bag+FIBRE DRUM

Supply Ability: 30MT/MONTH

Product Name: 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole; 6-bromo-4-fluoro-2-methyl-1-propan-2-ylbenzimidazole We, Shandong Haohong Biotechnology Co., Ltd. are manufacture of API and intermediates, Abemaciclib is our top strong...
Abemaciclib Intermediate Cas 1180132-17-5

Brand: HAOHONG

Packaging: PE BAG+Aluminum foil bag+FIBRE DRUM

Supply Ability: 30MT/MONTH

Product Name: 6-(2-chloro-5-fluoropyrimidin-4-yl)-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole; 6-(2-chloro-5-fluoropyrimidin-4-yl)-4-fluoro-1-isopropyl-2-methyl-1H-benzimidazole;...
Abemaciclib Intermediate Cas 1231930-42-9

Brand: HAOHONG

Packaging: PE BAG+Aluminum foil bag+FIBRE DRUM

Supply Ability: 30MT/MONTH

Product Name: 6-(2-chloro-5-fluoropyrimidin-4-yl)-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole; 6-(2-chloro-5-fluoropyrimidin-4-yl)-4-fluoro-1-isopropyl-2-methyl-1H-benzimidazole;...
Abemaciclib Intermediate Cas 1231930-37-2

Brand: HAOHONG

Packaging: PE BAG+Aluminum foil bag+FIBRE DRUM

Supply Ability: 30MT/MONTH

Product Name: 4-fluoro-1-isopropyl-2-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazole API name:Abemaciclib Intermediate CAS No.: 1231930-37-2 We, Shandong Haohong Biotechnology Co., Ltd. are manufacture of API and...
Home > Products > Anti-cancer Drug > Abemaciclib Intermediates

China Abemaciclib Intermediates Suppliers

Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. Abemaciclib specifically inhibits CDK4 and 6, thereby inhibiting retinoblastoma (Rb) protein phosphorylation in early G1. Inhibition of Rb phosphorylation prevents CDK-mediated G1-S phase transition, thereby arresting the cell cycle in the G1 phase, suppressing DNA synthesis and inhibiting cancer cell growth. Overexpression of the serine/threonine kinases CDK4/6, as seen in certain types of cancer, causes cell cycle deregulation.

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